IA Neurofibromatosis, or NF, is the most common neurological disorder caused by a single gene.B. Two types: NF1 and NF21. NF1: affects 1 in 4,0002 people. NF2- affects 1 in 50,000 people. Inherited and autosomal D. May be potentially fatalE. The Elephant Man, Joseph Merrick, was thought to have NF, but he actually had Proteus F syndrome. Neurofibromatosis is a unique disease because it is incurable, can be severely disfiguring, and can be benign or terminal.II.A. NF is caused by a mutation in the NF1 gene, which creates the protein neurofibromin.B. It is a potentially dangerous disorder1. No cure or treatment2. Some neurofibromas, or tumors, can be removed surgicallyC. Around the 1990s there was excitement because scientists had discovered the gene that caused the diseaseD. However, they have not found a cure1. Surgical removal of tumors is a viable option, but it is not a cure2. “…Fast-growing tumors are removed as they may become malignant...
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