1.0 Definition of Biotechnology In the beginning, prehistoric man became intellectual enough to breed animals and plants and collect various herbs to produce medicines, bread, wine, beer and other fermented foods, i.e. yogurt, cheese and so on. Biotechnological terms usually refer to the use of living organisms or their products to prevent human health and the environment with a superior disposition (Peters, 1993). Furthermore, biotechnology refers to any technique that uses living organisms to compose or modify products and services for particular purposes (Murugan & Wins, 2010). The application of biological organisms, systems and processes to the provision of goods and services is described as modern biotechnology in the world (Teusink & Smid, 2006; Nga, 2005 as cited in Murugan & Wins, 2010). According to many scholars, biotechnology is a significant and massive terrain of science and technology. It embraces multidisciplinary inputs, namely biochemistry, genetics, microbiology, cell biology and other disciplines. Furthermore, biotechnology is divided into three types: red biotechnology (medicine and healthcare problems), green biotechnology (agriculture problems) and white biotechnology (industrial production). According to the European Biotechnology Federation (EFB), biotechnology defined as the integration of natural resources sciences and organisms, cells and molecular analogues for goods and services (Smith, 2004). Furthermore, the purpose of this federation is to develop biotechnological processes, promote awareness in society and provide government bodies with information on biotechnology (Smith, 2004). This federation promotes competitive development and greater mobilization among society. 2.0 Scenario on Bio...... half of the document ...... asio-based ethanol as a raw material is still under research and development (Morita et al, 2007) . Although the Japanese biodiesel market is small, it has the potential to grow given the magnitude of total diesel demand and the use of biodiesel as a substitute (Iijima, 2013). Research is currently underway to study algae as a potential feedstock for biofuel production. Although Malaysia and Japan have used different raw materials to produce biofuel, we can conclude that both countries use their own resources and conduct extensive research to produce biofuels in a more economical and environmentally friendly way. way.3.0 ConclusionIn conclusion, biotechnology sectors in Malaysia are overall lagging behind some Asian countries such as Japan. But the TPPA, Trans Pacific Partnership Agreement, was made for the economic growth of Malaysia, thus also increasing the productivity of the biotechnology sector in Malaysia.