Although the two texts included men of questionable science, their methods of experimentation were different. Determined to separate the two sides of man, Jekyll took on the role of laboratory rat. He was fully aware of the risks involved in self-experimentation, as he states: “I knew well that I was risking death; for any drug that so powerfully controlled and shook the very fortress of identity, could, with the slightest qualm of overdose or at least inexpediency at the time of exposure, completely obliterate that immaterial tabernacle that I hoped would change. But the temptation of such a singular and profound discovery has finally overcome the suggestions of alarm” (44). Despite all the risky possibilities, Jekyll's drive for scientific discovery pushed him forward. Although Jekyll's methods were more practical, Rappaccini took more precautions. Rappaccini has adopted all the necessary rules to avoid any damage to himself. For example, when he spent time in his poisonous garden, “…he defended his hands with a pair of thick gloves…and he put a kind of mask over his mouth and nostrils…” (2). Rappaccini preferred to perform his experiments on other people such as Beatrice or Giovanni, rather than on himself. Another difference between Jekyll and Hyde and Rappaccini's daughter was the terms of confinement. Both Jekyll and Beatrice were kept away from society, but for different reasons