Case Study . The mutation can affect transcription and translation, because it modifies the genetic sequence and the structure of proteins. The mutation affects transcription because it changes the amino acid sequence and destroys the function of the protein. Likewise, the mutation affects translation because it intervenes in the process of mRNA translation and in the cellular components that control them (Scheper, Van der Knaap, & Proud, 2007). As a result, disorders occur when mutations alter the process of transcription and translation. Similarly, xeroderma pigmentation is the result of a mutation in genes responsible for repairing damaged cells (Genetic Home Reference, 2015). In normal cells, DNA damaged by toxic chemicals and UV rays is repaired before it causes problems. This is not the case with XP; the accumulation of unrepaired damaged cells can lead to the symptoms of xeroderma

Topic > Case Study . The mutation can affect transcription and translation, because it modifies the genetic sequence and the structure of proteins. The mutation affects transcription because it changes the amino acid sequence and destroys the function of the protein. Likewise, the mutation affects translation because it intervenes in the process of mRNA translation and in the cellular components that control them (Scheper, Van der Knaap, & Proud, 2007). As a result, disorders occur when mutations alter the process of transcription and translation. Similarly, xeroderma pigmentation is the result of a mutation in genes responsible for repairing damaged cells (Genetic Home Reference, 2015). In normal cells, DNA damaged by toxic chemicals and UV rays is repaired before it causes problems. This is not the case with XP; the accumulation of unrepaired damaged cells can lead to the symptoms of xeroderma